Sufentanil induction dose range

Sufentanil induction dose range

• A. 1-3 mcg/kg
• B. 0.01-0.03 mcg/kg
• C. 0.1-0.3 mcg/kg
• D. 0.5-1 mcg/kg

Answer: (C)

Sufentanil has very high potency, so the induction dose is usefully small. The goal during induction is to blunt the hemodynamic and analgesic responses to laryngoscopy and intubation without causing significant respiratory depression or chest wall rigidity. A dose in the range of 0.1–0.3 mcg/kg provides effective analgesia and autonomic stability when used with an induction agent like propofol, while minimizing adverse effects. Doses higher than this increase the risk of respiratory depression and chest wall rigidity, and doses much lower may not adequately blunt the stress response.

Sufentanil has very high potency, so the induction dose is usefully small. The goal during induction is to blunt the hemodynamic and analgesic responses to laryngoscopy and intubation without causing significant respiratory depression or chest wall rigidity. A dose in the range of 0.1–0.3 mcg/kg provides effective analgesia and autonomic stability when used with an induction agent like propofol, while minimizing adverse effects. Doses higher than this increase the risk of respiratory depression and chest wall rigidity, and doses much lower may not adequately blunt the stress response.